StemCellIVFTreatment—RegenerativeMedicineApproach
Written & medically reviewed by Dr. Shaivalini Kamarapu
MBBS · MS (Obstetrics & Gynaecology) · Fellowship in Reproductive Medicine · 20+ years of clinical experience
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StemcellIVFtreatment—aregenerativemedicineapproach
Every woman is born with a fixed number of eggs. As age advances, the number of eggs decreases — leading to difficulty in conception, especially after 35 years of age. In such conditions, the options available are a donor egg (from another woman) or stem cell therapy. The success rate of stem cell therapy is variable, and can be up to 50%.
Whatarestemcells?
Stem cells are cells which have:
Ability of unlimited self renewal
Ability of differentiation (to give rise to a specialised cell type that becomes part of a healthy person)
Multipotent stem cells can be harvested from the bone marrow of the patient.
Types of stem cells
Embryonic
Non-Embryonic
Induced Pluripotent
Techniques used in stem cell treatment
Suspension Technology
Inhibitor Differentiation Method
Whataretheusesofstemcelltherapyingynaecology?
Cases of infertility treated with stem cell therapy include:
Premature ovarian failure (inability of a woman to form eggs)
Testicular failure (inability of a male to form sperm)
Asherman's syndrome (uterine synechia — when walls of the uterine cavity stick to each other, compromising the cavity space)
Whatistheroleofstemcelltherapyinprematureovarianfailure?
Stem cell preparation is injected laparoscopically into the ovary. American studies have shown an increase in ovarian size and a 2-fold increase in estrogen levels (female hormone levels) for up to 1 year after the procedure.
Relief in symptoms of POF such as hot flushes, night sweats, decreased libido, vaginal dryness, and repeated urinary infections has been seen, leading to enhanced quality of life.